Solution:

In the majority of situations, Advantage will work with multiple network card setups in servers. In cases where your server is connected to multiple networks and/or has multiple IP addresses or has a special configuration in which communication with Advantage is not occuring properly, it would be wise to first check your routing tables as well as other network configurations that could be hindering communication.

If the problem is still persisting after checking the setup of your network, there is a setting available that will force Advantage to use the network card associated with a specific IP address.